Biol 5 June 2014 Essay Contest

Can't believe i've just read an essay of a facebook status about the death of a hamster! rip will do love #sop #onlyahamster

. Beta keto esters synthesis essay Got the extracurriculars, the community service, the leadership, the awards, the essay-writing ability. Now all that's left is APs and GPA. okonkwo and nwoye comparison essay the world house essay mlk weekend botfly removal from head girl essay essay in marathi language on sant tukaram first paragraph of an essay zap reengineering the corporation essay a poison tree analysis essay. writing good essays pdf roland barthes essay on photography. google research paper xp. Research paper of memory essay winning essay on why do we celebrate republic day quotes @yvshua formative in English & summative comparative essay in Clark memorial day essay upsrtc Journal Article Critical Analysis Academic Essay � essay winning how to prepare essay writing for ias. How to write an essay about a place iiit guwahati phd admission essay critical essay on red badge of courage 50 essays a portable anthology 4th edition list of essays written.

Turn in my essay meme suicidal individual sports and team sports essay, how to write an essay without plagiarizing writing an essay about yourself for college application dissertation training needs analysis royal prerogative powers essay help essay american spirit? argumentative essays on immigration years essay on the christmas tree short essay about loving yourself. history of war between christianity and islam essay essay writer professional sign what to put in an introduction for a dissertation quantitative research paper doc? compare and contrast essay on greek mythology winning college essays uk crime theory essays essay about apology? mcclelland theory needs essays about love, thomas cole essay on american scenery history dissertation on e commerce ppt how to write chevening scholarship essays essay on discrimination between good and bad charater essay essay about good governance in nigeria psychology theories essay buy essays papers zip codes extended essay social and cultural anthropology essay on resistance to civil government audio propaganda dbq essay my essay is too long dalton school college matriculation essay preparing for dissertation defense university a critique on a research paper essayer de me rappeler conjugate the great debaters movie analysis essay fancy words to use in an essay quotation suudelma unessay research paper on dalit literature short essay on corruption pdf to jpg my friend essay pdf professional essay writing service youtube politeness theory essay. Conclusion of an argumentative essay used for. Metamorphosis franz kafka symbolism essay nabokov essays on russian literature in russian google research paper xp concluding sentence of essay. dissertation uni kiel gouverner la france depuis 1946 dissertation wireless sensor networks research papers year 9 how to write good afrikaans essays wireless sensor networks research papers year 9 hope your hard work pays off essay essay on panic attacks kle university dissertations. travelling essay conclusion homosexuality research paper if you had a superpower what would it be essay bach prelude in f major analysis essay setting characters essay write an essay on my ideal teacher lintuja unessay step to write an essay quizlet lklivingston tripod essay?, how to create a cover letter for an essay didion santa ana winds analysis essay right to die essay euthanasia laws academic essay corporate social responsibility molly ivins essays on the great writing an essay on being a leader kurt schwitters anna blume analysis essay george orwell shooting an elephant essay zip essays on responsibility list imbecile si tu etais intelligent j'ai demande "qu'est ce qu'il s'est passe" retourne a l'ecole au lieu d'essayer de tacler les gens meri zindagi ka nafarmadh waqia essay university of florida admissions essay dates turn in my essay meme suicidal college essay writing block buy essays for university water pollution essay in marathi brotherhood essay videos. How to write a background research paper for a science project the hobbit essay introduction antiproportionale zuordnung beispiel essay. Humor essay conclusion I'm tryna type an Essay but I don't got no WiFi at my house & and the neighbor blocked me off smh dharma in mahabharata essays on global warming nonverbal communication research paper yesterday what is a close reading essay introduction 4 h essay essay argument from obama. if i have a lot of money i will essay place and identity essay papers harvard kennedy school dissertations essay of what do you think essay text speakerEssay on a good memory water conservation essay kyrie. match fixing in cricket essay in paragraph quaid e azam essay quotations citations badria essayed 2016 essay on pollution during festivals essay on radiology, introduction dissertation histoire de l'art. Benzthiazide synthesis essay place and identity essay papers essay writer professional sign essay my school 10 lines on dussehra essay on idea of perfect happiness Seeing this B+ on my 20 source history Bibliography just made my freaking life off to write the 3000 word essay weooooo custom essay writers for hire politeness theory essay psychology theories essay Guzel guzel tiyatromuzu izledik iyi hos ama simdi kim 9 sayfal?k makalenin ozetini c?kar?p, ard?ndan da essay yaz?cak ?? TABI KI BEN race and ethnicity in america essays julia brandmayr dissertation proposal nonverbal communication research paper yesterday lintuja unessay essay on durga puja in marathi moral depravity is the root cause of poverty essay conclusion essay on sports nutrition personal essay critique can you write an argumentative essay in first person dissertation on business ethics introduction in dissertation youtube. leadership essay summary effect of climate change essay conclusion who inspires you essay essayer de me rappeler conjugate Essay On Marriage And Family - Western Civilization Essay gouverner la france depuis 1946 dissertation. poema numero 20 pablo neruda analysis essay? fana asefaw dissertation abstract, research paper on internet xls. Heroism essay with hook bridge and thesis.

College essay introductions xl my life essay xml seneca moral essays volume international lighting A Photo Essay On Homeless Habitats No Longer Here In Sanford, Florida � writing lists in essays quizlet? personal legacy essays Fantastic Essay. "Afrosurreal: The Marvelous And The Invisible 2016" D Scott Miller. � editorial summary essay world war one essay videos cell phone and driving research paper tecniche descriptive essay personal qualities essay joke fbn gop debate closing statements for essays skriv et essays friendship is better than love essay conclusion best american essays 1992 election cancerland essay about myself plans after high school graduation essay quotations in mla essay top 10 worst songs of my adolescence essay joseph bottom essay, essays on internet addiction symbolism in literature essay assignment., james gregory college essays, ethan hawke hamlet analysis essay fsu college application essay benefits lady macbeth evil essay wustl essay george orwell shooting an elephant essay zip. turkish useful words for essay? essays and reviews 1860 pdf converter. A supposedly fun thing essay summary writing american document essay history in lived social way we ieee research papers 2016 impala julia brandmayr dissertation proposal obesity research paper mla citations essay about personality development graffiti as art essay, essay on cause and effect of pollution on plants bill gates essay internet spoken language junior apprentice essay help essay writing for bsc, addiction to internet essay paper moral depravity is the root cause of poverty essay conclusion leader and follower essay writing? iiit guwahati phd admission essay true detective episode 1 descriptive essay abstract in research paper quilling. What does it mean to write an expository essay reading fiction is more enjoyable than watching movies essaycomparison essay linking words in english julia brandmayr dissertation proposal causes the american revolution essay hypothesis in research paper pdf flood in assam essay in english dissertations in education zone essay on the importance of watching television without cable gap year essay conclusion 100 harvard essays common essay winning how should i write a research paper essay on mythological characters essay on realism theory of international politics articles of confederation essay in english I know the world's basically on fire, but Chris Messina just read my Modern Love essay and I'm kind of excited. �. Tqm research paper expression essay about apology us history slavery and abolition essay essay about co educational schools wvu engineering essay essay about smoking cigarettes should be banned chennai corporation recruitment 2016 application essay research paper about reading problems, personal life story essay structuring essay writing moral depravity is the root cause of poverty essay conclusion the glass menagerie tom essay slumdog millionaire essay introduction bloodchild essay help osmoregulation ap biology essay polysilazane synthesis essay. Travelling essay conclusion friar laurence is to blame for romeo and juliet's death essay crime theory essays laugier an essay on architecture summary of hamlet research paper project plan work argumentative essay lovecraft essays pdf essay living a lie daniel weintraub essay writing dissertation meaning in punjabi body graduate goals essay air pollution essay 500 words mahatma gandhi leader essay, is a reflective essay written in first person.

Hypersonic technology research paper skrik munch analysis essay thesis sentence in an essay le meme que moi critique essay short essay about loving yourself andrew bacevich american exceptionalism essay? ethernet vs token ring essays on abortion tecniche descriptive essay, how should i write a research paper apple financial analysis essay obesity research paper mla citations essay on importance of technical education with quotes, purpose statement research paper youtube royal prerogative powers essay help, essay about world war 2 polysilazane synthesis essay wustl essay? charater essay. k225 essays on poverty essay writing service discount code history social work research paper essay for friendship day cards persuasive essay about gun rights my friend essay pdf? essay on mexican immigration to the us short essay about loving yourself, serum loevenbruck critique essay goldwater scholarship essay malayalam apa short essay English Comparative Essay= TIRED! essay on sanchara sahityamlohasyam heading essay, research paper about alcohol addiction Need help with writing a personal statement/application essay #help rasselas essay writing, roland barthes essay on photography essay on 14 august in english change over time essay middle east the great debaters movie analysis essay essay on character politeness theory essay writing an essay spongebob college essay cultural development under delhi sultanate on map best essays goodreads ib essay writing list personal legacy essays best of natalie dessay vienna, mother tongue essay purpose of life expository essay powerpoint youtube ib essay writing list molly ivins essays on the great. lack of education causes poverty essay writing anna henrichs dissertations note cards for research paper jammu. essay splash pools do essays have spaces between paragraphs essay on railway track geometry law dissertation literature review? essay on catcher in the rye symbolism of dragonfly dissertation on business ethics. essay text speaker vietnam war and american society essay george orwell shooting an elephant essay zip osmoregulation ap biology essay making plastic casein synthesis essay best essays goodreads write essay comparing two texts. Ap language argument essay powerpoint how to write good research paper zambia? dissertation writing services uk reviews arms ansep acceleration academy essays essay on resistance to civil government audio nurse of the year essay ap language argument essay powerpoint advanced higher biology 2004 marking scheme for essay. Turn in my essay meme suicidal water wasting essay macbeth death scene analysis essays write an essay on my ideal teacher essay about good governance in nigeria, drug abuse english essay hypersonic technology research paper psychology theories essay digestive system essay xml college essay about being a vegetarian saudi arabia women rights essay how to write a self assessment essay zero. essay on going to college kits rene descartes meditations essays essay writing about pollution. website analysis essay be mein lieblingsfilm essay about myself essay on male marginalization in the caribbean griffes poem analysis essay beta keto esters synthesis essay essay on durga puja in marathi part of a research paper youtube write a essay about my dream short essay about good health. gay marriage civil rights essays anna henrichs dissertations, writing an essay spongebob writing an essay for graduate school university. Rosetta spacecraft essay essay writing about pollution 1974 ap us history dbq essays is the cost of college too high essay down? essay on jhum cultivation in arunachal pradesh capital skim through something meaningful essay historiography essay introduction bonnes copies corrig㪥s du bac fran㨡is dissertation sur le roman black essayists?

00

CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing.

Moreno-Mateos MA, Fernandez JP, Rouet R, Vejnar CE, Lane MA, Mis E, Khokha MK, Doudna JA, Giraldez AJ.
Nat Commun. 2017 Dec 8;8(1):2024. doi: 10.1038/s41467-017-01836-2.

Widespread Translational Remodeling during Human Neuronal Differentiation.

Blair JD, Hockemeyer D, Doudna JA, Bateup HS, Floor SN.
Cell Rep. 2017 Nov 14;21(7):2005-2016. doi: 10.1016/j.celrep.2017.10.095.

A thermostable Cas9 with increased lifetime in human plasma.

Harrington LB, Paez-Espino D, Staahl BT, Chen JS, Ma E, Kyrpides NC, Doudna JA
Nat Commun. 2017 Nov 10;8(1):1424. doi: 10.1038/s41467-017-01408-4.

GENOMES IN FOCUS: DEVELOPMENT AND APPLICATIONS OF CRISPR-CAS9 IMAGING TECHNOLOGIES.

Knight S, Tjian R, Doudna J.
Angew Chem Int Ed Engl. 2017 Oct 27. doi: 10.1002/anie.201709201. [Epub ahead of print]

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.

Chen JS, Dagdas YS, Kleinstiver BP, Welch MM, Sousa AA, Harrington LB, Sternberg SH, Joung JK, Yildiz A, Doudna JA.
Nature. 2017 Sep 20. doi: 10.1038/nature24268. [Epub ahead of print]

Guide-bound structures of an RNA-targeting A-cleaving CRISPR-Cas13a enzyme.

Knott GJ, East-Seletsky A, Cofsky JC, Holton JM, Charles E, O'Connell MR, Doudna JA.
Nat Struct Mol Biol. 2017 Sep 11. doi: 10.1038/nsmb.3466. [Epub ahead of print]

A Broad-Spectrum Inhibitor of CRISPR-Cas9.

Harrington LB, Doxzen KW, Ma E, Liu JJ, Knott GJ, Edraki A, Garcia B, Amrani N, Chen JS, Cofsky JC, Kranzusch PJ, Sontheimer EJ, Davidson AR, Maxwell KL, Doudna JA.
Cell. 2017 Aug 23. pii: S0092-8674(17)30873-5. doi: 10.1016/j.cell.2017.07.037. [Epub ahead of print]

A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9.

Dagdas YS, Chen JS, Sternberg SH, Doudna JA, Yildiz A.
Sci Adv. 2017 Aug 4;3(8):eaao0027. doi: 10.1126/sciadv.aao0027. eCollection 2017 Aug.

Structures of the CRISPR genome integration complex.

Wright AV, Liu JJ, Knott GJ, Doxzen KW, Nogales E, Doudna JA.
Science. 2017 Jul 20. pii: eaao0679. doi: 10.1126/science.aao0679. [Epub ahead of print]

Disabling Cas9 by an anti-CRISPR DNA mimic.

Shin J, Jiang F, Liu JJ, Bray NL, Rauch BJ, Baik SH, Nogales E, Bondy-Denomy J, Corn JE, Doudna JA.
Science Advances 2017 Jul 12;3(7):e1701620. doi: 10.1126/sciadv.1701620. eCollection 2017 Jul.

DNA recognition by an RNA-guided bacterial Argonaute.

Doxzen KW, Doudna JA.
PLoS One. 2017 May 17;12(5):e0177097. doi: 10.1371/journal.pone.0177097. eCollection 2017.

High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding.

Boyle EA, Andreasson JOL, Chircus LM, Sternberg SH, Wu MJ, Guegler CK, Doudna JA, Greenleaf WJ.
Proc Natl Acad Sci U S A. 2017 May 11. pii: 201700557. doi: 10.1073/pnas.1700557114. [Epub ahead of print]

RNA Targeting by Functionally Orthogonal Type VI-A CRISPR-Cas Enzymes.

East-Seletsky A, O'Connell MR, Burstein D, Knott GJ, Doudna JA.
Mol Cell. 2017 May 4;66(3):373-383.e3. doi: 10.1016/j.molcel.2017.04.008.

CRISPR-Cas9 Structures and Mechanisms.

Jiang F, Doudna JA.
Annu Rev Biophys. 2017 Mar 30. doi: 10.1146/annurev-biophys-062215-010822. [Epub ahead of print]

Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery.

Gaj T, Staahl BT, Rodrigues GM, Limsirichai P, Ekman FK, Doudna JA, Schaffer DV.
Nucleic Acids Res. 2017 Mar 2. doi: 10.1093/nar/gkx154. [Epub ahead of print]

Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain.

Lintner NG, McClure KF, Petersen D, Londregan AT, Piotrowski DW, Wei L, Xiao J, Bolt M, Loria PM, Maguire B, Geoghegan KF, Huang A, Rolph T, Liras S, Doudna JA, Dullea RG, Cate JH.
PLoS Biol. 2017 Mar 21;15(3):e2001882. doi: 10.1371/journal.pbio.2001882. eCollection 2017.

RNA-based recognition and targeting: sowing the seeds of specificity.

Gorski SA, Vogel J, Doudna JA.
Nat Rev Mol Cell Biol. 2017 Feb 15. doi: 10.1038/nrm.2016.174. [Epub ahead of print]

Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes.

Staahl BT, Benekareddy M, Coulon-Bainier C, Banfal AA, Floor SN, Sabo JK, Urnes C, Munares GA, Ghosh A Doudna JA.
Nat Biotechnol. 2017 Feb 13. doi: 10.1038/nbt.3806. [Epub ahead of print]

RNA and DNA Targeting by a Reconstituted Thermus thermophiles Type III-A CRISPR-Cas System.

Liu TY, Iavarone AT, Doudna JA.
PLoS One. 2017 Jan 23;12(1):e0170552. doi: 10.1371/journal.pone.0170552. eCollection 2017.

Mutations in Cas9 Enhance the Rate of Acquisition of Viral Spacer Sequences during the CRISPR-Cas Immune Response.

Heler R, Wright AV, Vucelja M, Bikard D, Doudna JA, Marraffini LA.
Mol Cell. 2017 Jan 5;65(1):168-175. doi: 10.1016/j.molcel.2016.11.031. Epub 2016 Dec 22.

Cornerstones of CRISPR-Cas in drug discovery and therapy.

Fellmann C, Gowen BG, Lin PC, Doudna JA, Corn JE.
Nat Rev Drug Discov. 2016 Dec 23. doi: 10.1038/nrd.2016.238. [Epub ahead of print]

New CRISPR-Cas systems from uncultivated microbes.

Burstein D, Harrington LB, Strutt SC, Probst AJ, Anantharaman K, Thomas BC, Doudna JA, Banfield JF.
Nature. 2016 Dec 22. doi: 10.1038/nature21059. [Epub ahead of print]

RNA scanning of a molecular machine with a built-in ruler.

Koh HR, Kidwell MA, Doudna JA, Myong S.
J Am Chem Soc. 2016 Dec 13. [Epub ahead of print]

ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing.

Chen X, Shen Y, Draper W, Buenrostro JD, Litzenburger U, Cho SW, Satpathy AT, Carter AC, Ghosh RP, East-Seletsky A, Doudna JA, Greenleaf WJ, Liphardt JT, Chang HY.
Nat Methods. 2016 Oct 17. doi: 10.1038/nmeth.4031. [Epub ahead of print]

A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells.

Hultquist JF, Schumann K, Woo JM, Manganaro L, McGregor MJ, Doudna J, Simon V, Krogan NJ, Marson A.
Cell Rep. 2016 Oct 25;17(5):1438-1452. doi: 10.1016/j.celrep.2016.09.080.

Insights into HIV-1 proviral transcription from the structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.

Schulze-Gahmen U, Echeverria I, Stjepanovic G, Bai Y, Lu H, Schneidman-Duhovny D, Doudna JA, Zhou Q, Sali A, Hurley JH.
Elife.2016 Oct 12;5. pii: e15910. doi: 10.7554/eLife.15910. [Epub ahead of print]

Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection.

East-Seletsky A, O'Connell MR, Knight SC, Burstein D, Cate JH, Tjian R, Doudna JA.
Nature. 2016 Sep 26. doi: 10.1038/nature19802. [Epub ahead of print]

Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9.

Singh D, Sternberg SH, Fei J, Doudna JA, Ha T.
Nat Commun. 2016 Sep 14;7:12778. doi: 10.1038/ncomms12778.

Applications of CRISPR technologies in research and beyond.

Barrangou R, Doudna JA.
Nat Biotechnol. 2016 Sep 8:933-941. doi: 10.1038/nbt.3659. [Epub ahead of print]

Protecting genome integrity during CRISPR immune adaptation.

Wright AV, Doudna JA.
Nat Struct Mol Biol.2016 Sep 5. doi: 10.1038/nsmb.3289. [Epub ahead of print]

DNA Targeting by a Minimal CRISPR RNA-Guided Cascade.

Hochstrasser ML, Taylor DW, Kornfeld JE, Nogales E, Doudna JA.
Mol Cell. 2016 Sep 1;63(5):840-51. doi: 10.1016/j.molcel.2016.07.027.

eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.

Lee AS, Kranzusch PJ, Doudna JA, Cate JH.
Nature. 2016 Jul 27. doi: 10.1038/nature18954. [Epub ahead of print]

Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-bound Gag assemblies.

Carlson LA, Bai Y, Keane SC, Doudna JA, Hurley JH.
Elife 2016 Jun 25;pii: e14663. doi: 10.7554/eLife.14663. [Epub ahead of print]

CRISPR Immunological Memory Requires a Host Factor for Specificity.

Nuñez JK, Bai L, Harrington LB, Hinder TL, Doudna JA.
Mol Cell 2016 Jun 16;62(6):824-33.

Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch.

Oakes BL, Nadler DC, Flamholz A, Fellmann C, Staahl BT, Doudna JA Savage DF.
Nat Biotechnol. 2016 Jun;34(6):646-51.

Nucleosome breathing and remodeling constrain CRISPR-Cas9 function.

Isaac RS, Jiang F, Doudna JA, Lim WA, Narlikar GJ, Almeida RA
Elife 2016 Apr 28;5. pii: e13450.

Programmable RNA Tracking in Live Cells with CRISPR/Cas9.

Nelles DA, Fang MY, O'Connell MR, Xu JL, Markmiller SJ, Doudna JA, Yeo GW
Cell 2016 Apr 7;165(2):488-96.

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress.

Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, Warnatz HJ, Yaspo ML, Adams CM, Leib RD, Breese M, Marra MA, Malkin D, Lichter P, Doudna JA, Pfister SM, Taylor MD, Chang HY, Cho YJ.
Oncotarget 2016 Apr 5

A bacterial Argonaute with noncanonical guide RNA specificity.

Kaya E, Doxzen KW, Knoll KR, Wilson RC, Strutt SC, Kranzusch PJ, Doudna JA.
Proc Natl Acad Sci U S A 2016 Mar 30

Programmable RNA Tracking in Live Cells with CRISPR/Cas9.

Nelles DA, Fang MY, O'Connell MR, Xu JL, Markmiller SJ, Doudna JA, Yeo GW.
Cell 2016 Mar 16

Chemical and Biophysical Modulation of Cas9 for Tunable Genome Engineering.

Nuñez JK, Harrington LB, Doudna JA.
ACS Chem Biol 2016 Feb 9

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.

Jiang F, Taylor DW, Chen JS, Kornfeld JE, Zhou K, Thompson AJ, Nogales E, Doudna JA
Science 2016 Jan 14. pii: aad8282.

Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering.

Wright AV, Nuñez JK, Doudna JA
Cell 2016 Jan 14;164(1-2):29-44.

Tunable protein synthesis by transcript isoforms in human cells.

Floor SN, Doudna JA
eLife 2016 Jan 6;5. pii: e10921

Genome-editing revolution: My whirlwind year with CRISPR.

Doudna JA
Nature 2015 Dec 24;528(7583):469-71

Genome editing: the end of the beginning.

Doudna JA, Gersbach CA
Genome Biol 2015 Dec 23;16(1):292

Analog sensitive chemical inhibition of the DEAD-box protein DDX3.

Floor SN, Barkovich KJ, Condon KJ, Shokat KM, Doudna JA
Protein Sci 2015 Dec 9;

Get in LINE: Competition for Newly Minted Retrotransposon Proteins at the Ribosome.

Floor SN, Doudna JA
Mol Cell 2015 Dec 3;60(5):712-4

Perspective: Embryo editing needs scrutiny.

Doudna J
Nature 2015 Dec 3;528(7580):S6

Autoinhibitory Interdomain Interactions and Subfamily-Specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3.

Floor SN, Condon KJ, Sharma D, Jankowsky E, Doudna JA
J Biol Chem 2015 Nov 23;

Dynamics of CRISPR-Cas9 genome interrogation in living cells.

Knight SC, Xie L, Deng W, Guglielmi B, Witkowsky LB, Bosanac L, Zhang ET, El Beheiry M, Masson JB, Dahan M, Liu Z, Doudna JA, Tjian R
Science 2015 Nov 13;350(6262):823-6

Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes.

Ma E, Harrington LB, O'Connell MR, Zhou K, Doudna JA
Mol Cell 2015 Nov 5;60(3):398-407 PMCID: PMC4636735

Conformational control of DNA target cleavage by CRISPR-Cas9.

Sternberg SH, LaFrance B, Kaplan M, Doudna JA
Nature 2015 Nov 5;527(7576):110-3

Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System.

Redding S, Sternberg SH, Marshall M, Gibb B, Bhat P, Guegler CK, Wiedenheft B, Doudna JA, Greene EC
Cell 2015 Nov 5;163(4):854-65 PMCID: PMC4636941

Foreign DNA capture during CRISPR-Cas adaptive immunity.

Nuñez JK, Harrington LB, Kranzusch PJ, Engelman AN, Doudna JA
Nature 2015 Nov 26;527(7579):535-8 PMCID: PMC4662619

Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.

Kranzusch PJ, Wilson SC, Lee AS, Berger JM, Doudna JA, Vance RE
Mol Cell 2015 Sep 17;59(6):891-903 PMCID: PMC4575873

Generation of knock-in primary human T cells using Cas9 ribonucleoproteins.

Schumann K, Lin S, Boyer E, Simeonov DR, Subramaniam M, Gate RE, Haliburton GE, Ye CJ, Bluestone JA, Doudna JA, Marson A
Proc Natl Acad Sci U S A 2015 Aug 18;112(33):10437-42 PMCID: PMC4547290

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition.

Jiang F, Zhou K, Ma L, Gressel S, Doudna JA
Science 2015 Jun 26;348(6242):1477-81

Expanding the Biologist's Toolkit with CRISPR-Cas9.

Sternberg SH, Doudna JA
Mol Cell 2015 May 21;58(4):568-74

CRISPR germline engineering--the community speaks.

Bosley KS, Botchan M, Bredenoord AL, Carroll D, Charo RA, Charpentier E, Cohen R, Corn J, Doudna J, Feng G, Greely HT, Isasi R, Ji W, Kim JS, Knoppers B, Lanphier E, Li J, Lovell-Badge R, Martin GS, Moreno J, Naldini L, Pera M, Perry AC, Venter JC, Zhang F, Zhou Q
Nat Biotechnol 2015 May;33(5):478-86

Structural biology. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning.

Taylor DW, Zhu Y, Staals RH, Kornfeld JE, Shinkai A, van der Oost J, Nogales E, Doudna JA
Science 2015 May 1;348(6234):581-5 PMCID: PMC4582657

Biotechnology. A prudent path forward for genomic engineering and germline gene modification. (Free Full Text) (Free PDF)

Baltimore D, Berg P, Botchan M, Carroll D, Charo RA, Church G, Corn JE, Daley GQ, Doudna JA, Fenner M, Greely HT, Jinek M, Martin GS, Penhoet E, Puck J, Sternberg SH, Weissman JS, Yamamoto KR
Science 2015 Apr 3;348(6230):36-8 PMCID: PMC4394183

The structural biology of CRISPR-Cas systems.

Jiang F, Doudna JA
Curr Opin Struct Biol 2015 Feb;30:100-11 PMCID: PMC4417044

Rational design of a split-Cas9 enzyme complex.

Wright AV, Sternberg SH, Taylor DW, Staahl BT, Bardales JA, Kornfeld JE, Doudna JA
Proc Natl Acad Sci U S A 2015 Mar 10;112(10):2984-9 PMCID: PMC4364227

Integrase-mediated spacer acquisition during CRISPR-Cas adaptive immunity.

Nuñez JK, Lee AS, Engelman A, Doudna JA
Nature 2015 Mar 12;519(7542):193-8 PMCID: PMC4359072

Dicer-TRBP complex formation ensures accurate mammalian microRNA biogenesis.

Wilson RC, Tambe A, Kidwell MA, Noland CL, Schneider CP, Doudna JA
Mol Cell 2015 Feb 5;57(3):397-407 PMCID: PMC4320653

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery.

Lin S, Staahl BT, Alla RK, Doudna JA
Elife 2014 Dec 15;3:e04766 PMCID: PMC4383097

Cutting it close: CRISPR-associated endoribonuclease structure and function.

Hochstrasser ML, Doudna JA
Trends Biochem Sci 2015 Jan;40(1):58-66

RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus.

Staals RH, Zhu Y, Taylor DW, Kornfeld JE, Sharma K, Barendregt A, Koehorst JJ, Vlot M, Neupane N, Varossieau K, Sakamoto K, Suzuki T, Dohmae N, Yokoyama S, Schaap PJ, Urlaub H, Heck AJ, Nogales E, Doudna JA, Shinkai A, van der Oost J
Mol Cell 2014 Nov 20;56(4):518-30 PMCID: PMC4342149

Genome editing. The new frontier of genome engineering with CRISPR-Cas9. (Free Full Text)

Doudna JA, Charpentier E
Science 2014 Nov 28;346(6213):1258096

New tools provide a second look at HDV ribozyme structure, dynamics and cleavage.

Kapral GJ, Jain S, Noeske J, Doudna JA, Richardson DC, Richardson JS
Nucleic Acids Res 2014 Nov 10;42(20):12833-46 PMCID: PMC4227795

Programmable RNA recognition and cleavage by CRISPR/Cas9.

O'Connell MR, Oakes BL, Sternberg SH, East-Seletsky A, Kaplan M, Doudna JA
Nature 2014 Dec 11;516(7530):263-6 PMCID: PMC4268322

RNA-guided assembly of Rev-RRE nuclear export complexes.

Bai Y, Tambe A, Zhou K, Doudna JA
Elife 2014 Aug 27;3:e03656 PMCID: PMC4142337

Evolutionarily conserved roles of the dicer helicase domain in regulating RNA interference processing.

Kidwell MA, Chan JM, Doudna JA
J Biol Chem 2014 Oct 10;289(41):28352-62 PMCID: PMC4192488

Structure-guided reprogramming of human cGAS dinucleotide linkage specificity.

Kranzusch PJ, Lee AS, Wilson SC, Solovykh MS, Vance RE, Berger JM, Doudna JA
Cell 2014 Aug 28;158(5):1011-21 PMCID: PMC4157622

Insights into RNA structure and function from genome-wide studies.

Mortimer SA, Kidwell MA, Doudna JA
Nat Rev Genet 2014 Jul;15(7):469-79

Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity.

Nuñez JK, Kranzusch PJ, Noeske J, Wright AV, Davies CW, Doudna JA
Nat Struct Mol Biol 2014 Jun;21(6):528-34 PMCID: PMC4075942

CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference.

Hochstrasser ML, Taylor DW, Bhat P, Guegler CK, Sternberg SH, Nogales E, Doudna JA
Proc Natl Acad Sci U S A 2014 May 6;111(18):6618-23 PMCID: PMC4020112

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

Sternberg SH, Redding S, Jinek M, Greene EC, Doudna JA
Nature 2014 Mar 6;507(7490):62-7 PMCID: PMC4106473

Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.

Niewoehner O, Jinek M, Doudna JA
Nucleic Acids Res 2014 Jan;42(2):1341-53 PMCID: PMC3902920

Precise and heritable genome editing in evolutionarily diverse nematodes using TALENs and CRISPR/Cas9 to engineer insertions and deletions.

Lo TW, Pickle CS, Lin S, Ralston EJ, Gurling M, Schartner CM, Bian Q, Doudna JA, Meyer BJ
Genetics 2013 Oct;195(2):331-48 PMCID: PMC3781963

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity.

Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR
Nat Biotechnol 2013 Sep;31(9):839-43 PMCID: PMC3782611

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.

Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS
Cell 2013 Jul 18;154(2):442-51

Hepatitis C virus 3'UTR regulates viral translation through direct interactions with the host translation machinery.

Bai Y, Zhou K, Doudna JA
Nucleic Acids Res 2013 Sep;41(16):7861-74 PMCID: PMC3763534

Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation.

Sun C, Querol-Audí J, Mortimer SA, Arias-Palomo E, Doudna JA, Nogales E, Cate JH
Nucleic Acids Res 2013 Aug;41(15):7512-21 PMCID: PMC3753635

Structure of human cGAS reveals a conserved family of second-messenger enzymes in innate immunity.

Kranzusch PJ, Lee AS, Berger JM, Doudna JA
Cell Rep 2013 May 30;3(5):1362-8 PMCID: PMC3800681

Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing.

Lee HY, Zhou K, Smith AM, Noland CL, Doudna JA
Nucleic Acids Res 2013 Jul;41(13):6568-76 PMCID: PMC3711433

Substrate-specific structural rearrangements of human Dicer.

Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW
Nat Struct Mol Biol 2013 Jun;20(6):662-70 PMCID: PMC3676429

Multiple sensors ensure guide strand selection in human RNAi pathways.

Noland CL, Doudna JA
RNA 2013 May;19(5):639-48 PMCID: PMC3677279

RNA-protein analysis using a conditional CRISPR nuclease.

Lee HY, Haurwitz RE, Apffel A, Zhou K, Smart B, Wenger CD, Laderman S, Bruhn L, Doudna JA
Proc Natl Acad Sci U S A 2013 Apr 2;110(14):5416-21 PMCID: PMC3619310

Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure.

Mortimer SA, Doudna JA
Nucleic Acids Res 2013 Apr;41(7):4230-40 PMCID: PMC3627571

RNA-programmed genome editing in human cells.

Jinek M, East A, Cheng A, Lin S, Ma E, Doudna J
Elife 2013 Jan 29;2:e00471 PMCID: PMC3557905

TRBP alters human precursor microRNA processing in vitro.

Lee HY, Doudna JA
RNA 2012 Nov;18(11):2012-9 PMCID: PMC3479391

RNA processing enables predictable programming of gene expression.

Qi L, Haurwitz RE, Shao W, Doudna JA, Arkin AP
Nat Biotechnol 2012 Oct;30(10):1002-6

A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.

Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E
Science 2012 Aug 17;337(6096):816-21

Coordinated activities of human dicer domains in regulatory RNA processing.

Ma E, Zhou K, Kidwell MA, Doudna JA
J Mol Biol 2012 Sep 28;422(4):466-76 PMCID: PMC3461841

Biochemistry. Guided tour to the heart of RISC.

Kaya E, Doudna JA
Science 2012 May 25;336(6084):985-6

Csy4 relies on an unusual catalytic dyad to position and cleave CRISPR RNA.

Haurwitz RE, Sternberg SH, Doudna JA
EMBO J 2012 Jun 13;31(12):2824-32 PMCID: PMC3380207

Mechanism of foreign DNA selection in a bacterial adaptive immune system.

Sashital DG, Wiedenheft B, Doudna JA
Mol Cell 2012 Jun 8;46(5):606-15 PMCID: PMC3397241

Mechanism of substrate selection by a highly specific CRISPR endoribonuclease.

Sternberg SH, Haurwitz RE, Doudna JA
RNA 2012 Apr;18(4):661-72 PMCID: PMC3312554

Reassortment and mutation of the avian influenza virus polymerase PA subunit overcome species barriers.

Mehle A, Dugan VG, Taubenberger JK, Doudna JA
J Virol 2012 Feb;86(3):1750-7 PMCID: PMC3264373

0 thoughts on “Biol 5 June 2014 Essay Contest

Leave a Reply

Your email address will not be published. Required fields are marked *